Extracellular Electrophysiology Acquisition

Novmber 2024

Applications will open soon

COURSE OVERVIEW

Any data we collect has been shaped by the system we used to record it. Understanding the tools involved in data acquisition gives you the confidence to make informed experimental design choices, and the freedom to combine and try new approaches while building your dream setup.

In this course, we will develop your understanding of electrophysiology data acquisition. In terms of hardware, you will learn how acquisition systems can amplify tiny signals and filter out noise. You’ll test this understanding by building your own system to measure muscle and heart signals. In software, you will encounter synchronisation considerations, as we add incoming datastreams and build an increasingly complex experimental design.

Don’t be discouraged if you secretly panic at the mention of capacitance, this course starts from the very basics. Advanced students can make the final project as challenging as they like.

Designed by Open Ephys and Open Ephys Production Site, this course will have an open-source flavour and encourage you to try new ideas, share your insights, and connect with the open-source community.

WHAT WILL YOU LEARN?

By the end of the course, you will:

  • be familiar with the electronic building blocks of acquisition systems

  • be able to model and build circuits to amplify and filter incoming signals

  • be able to use the Bonsai programming language to stream data and run closed-loop experiments with multiple datastreams

FACULTY

DIRECTORS

Jakob Voigts

Course Director (MIT and Open Ephys, USA)

Cecilia Herbert

Course Director (Open Ephys Production Site, PT)​

Filipe Carvalho

Course Director (Open Ephys Production Site, PT)​

TEACHING ASSISTANTS

Every year we have an amazing group of Teaching Assistants who remotely help the students as they work on the course activities. Past TAs have been selected from institutes such as Champalimaud Foundation in Portugal, The Francis Crick Institute in the UK and the University of Buenos Aires in Argentina.

VIDEO LECTURES

The online lectures have been developed by Alex Leighton and Filipe Carvalho (Open Ephys Production Site, PT), Jakob Voigts (MIT and Open Ephys, USA), and Joana Neto (FCT NOVA, PT).

COURSE DESIGNERS

This course was brought to life thanks to the remarkable work of Alex Leighton as course director for the first three editions, with the vision of course director Jakob Voigts and co-director Filipe Carvalho and the help of Aarón Cuevas López (Universitat Politècnica de València, ES and Open Ephys Production Site, PT), Joana Neto (FCT NOVA, PT), Jonathan P. Newman (MIT and Open Ephys, USA) and Josh Siegle (Allen Institute, USA).

PROGRAMME

Day 1 – Introduction

You will learn:

  • What are we trying to measure? Electrical signals in the brain and ways to record them.

  • How can we collect these signals without changing them? Considerations when building an acquisition system.

  • Using a simulator to visualise electrical circuits online and make predictions about real-world circuits.

  • Using the breadboard and components in your kit to test your understanding of electronics concepts.

Day 2 – Impedance

Using microcontrollers to acquire physiological data.

  • What is impedance? Understanding how we protect our signals while measuring them.

  • Understanding the function and limitations of operational amplifiers.

Day 3 – Data Acquisition

Understanding Instrumentation Amplifiers.

  • Simulating, building and testing low & high-pass filters.

  • Visualise your own EMG/ECG data using the Bonsai programming language.

Day 4 – Synchronizing Datastreams

Expanding on Bonsai – controlling cameras, receiving other datastreams.

  • Understanding closed-loop experiments, timestamp considerations, and synchronising datastreams.

  • Designing student projects and group feedback on plan.

Day 5 – Project and Open-Source Neuroscience

Open Ephys – open-source hardware & software development.

  • An overview of open-source community projects.

  • Student project presentation.

APPLY

Applications are still closed but you can express your interest in the next edition by clicking on the button below and filling in the form. 

Registration fee

  • Individual: 500€ per person (includes shipping of the course kit, pre-recorded and live lectures before and during the course, full attendance to the course, and course certificate).

  • Group: 500€ for one person and one course kit + 150€ for any additional person (without the course kit)

Stipends (waived partial or full registration fee).

SPONSORS

This course has been kindly supported by the following sponsors and partners:

ATOMS

ELECTRONS

MAGNETS

LIGHT

SENSORS

MOTORS

TRANSISTORS

FPGAs

MEMORY

LOGIC

DATA

POWER

ATOMS ELECTRONS MAGNETS LIGHT SENSORS MOTORS TRANSISTORS FPGAs MEMORY LOGIC DATA POWER